Products
SIRT1 antibody
- SPECIFICATIONS
- CITATIONS
- Product Name
- SIRT1 antibody
- Catalogue No.
- FNab07877
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- sirtuin (silent mating type information regulation 2 homolog) 1
- Alternative Names
- hSIR2 antibody, hSIRT1 antibody, SIR2 like protein 1 antibody, SIR2L1 antibody, SIRT1 antibody
- UniProt ID
- Q96EB6
- Observed MW
- 130 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP: 1:50 - 1:100
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab07877( SIRT1 Antibody) at dilution of 1:1000
IP Result of anti-SIRT1 (IP:FNab07877, 4ug; Detection:FNab07877 1:500) with mouse testis tissue lysate 8000ug.
Immunohistochemistry of paraffin-embedded mouse testis tissue slide using FNab07877( SIRT1 Antibody) at dilution of 1:100
- Background
- This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
IF: 8
- Journal:
- Cellular and Molecular Life Sciences
- Author:
- Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, Shaanxi, China.
- Sample:
- cytoplasmic lysate
- Cited Date:
- 2024-05-17
- Product: